Ataxin 1 anticorps

N° du produit ABIN865485

Cet anticorps anti-Ataxin 1 est un anticorps Souris Monoclonal détectant Ataxin 1 dans WB, IHC, ELISA, IF et FACS. Adapté pour Humain.

Aperçu rapide pour Ataxin 1 anticorps (ABIN865485)

Antigène: Ataxin 1 (ATXN1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ataxin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2F5

Détail du produit anti-Ataxin 1 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ATXN1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, FC: 1/200-1/400 ELISA: Propose dilution 1/10000. Figure 3: Immunofluorescence

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur Ataxin 1

Antigène: Ataxin 1 (ATXN1)

Autre désignation: ATXN1

Sujet: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. Synonyms: ATX1, SCA1, D6S504E, ATXN1

Poids moléculaire: 87kDa

ID gène: 6310

Pathways: Synaptic Membrane